Summary: The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear.Here, we demonstrate that two C.elegans THAP domain proteins, LIN-15B and LIN-36, co-localize with DREAM and function by different mechanisms fo
Machine learning methods have been remarkably successful for a wide Jumbo OFC range of application areas in the extraction of essential information from data.An exciting and relatively recent development is the uptake of machine learning in the natural sciences, where the major goal is to obtain novel scientific insights and discoveries from observ
An optimal Drone control problem for discrete systems is considered.A method of successive improvements along with its modernization based on the expansion of the main structures of the core algorithm about the parameter is suggested.The idea of the method is based on local approximation of attainability set, which is described by the zeros of the
Gene-edited dogs are promising models for biomedical research because they have hundreds of genetic diseases that are similar to humans.A common method for producing gene-edited dogs is assisted reproductive technology (ART) using in vivo oocytes or embryos, but it is much more inefficient and has a higher cost.ART for dogs has lagged mostly becaus